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A few children stated that they applied pesticides to tobacco plants with a handheld sprayer and backpack, or operated tractors that were spraying pesticides on tobacco fields.[93] Children also reported experiencing a range of symptoms after coming into contact with pesticides while working in tobacco farming, including burning eyes, burning nose, itchy skin, nausea, vomiting, dizziness, shortness of breath, redness and swelling of the mouth, and headaches

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That made it difficult to assess whether the carcinogen found in the urine was actually from the e-cigarette use or from the cigarette use. Further research is needed, said Bjurlin, who wants to determine the threshold of exposure to carcinogens that would lead to development of bladder cancer or other cancer types

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